EFFECT OF IODINE DOSES ON HEMATOLOGICAL AND ENZYMES PARAMETERS OF BLACK GOATS DURING LATE PREGNANCY PERIOD
Keywords:
Iodine drenching; Late pregnancy; Black goats; Hematology; Enzymes
Abstract
The aim of the present study was to evaluate the effect of Iodine supplementation in drinking water on blood hematology and enzyme parameters in Black goats during late pregnancy. Twenty-four pregnant local black goats were used in the present study. Each goat’s was drenched with potassium iodide with 0 mg I/day (control; C), 0.50 mg I/day (treatment one; T1) as low iodine group and 1.00 mg I/day (treatment two; T2) as high iodine group. Blood samples were collected weekly from six weeks before parturition from goats and 1st week of ages of kids. Blood samples were analyzed for hematology and enzymes parameter. Hematological parameters of goats include RBC (106/µL), WBC (103/µL), HB (g/dL), PLT (103/µL), HCT (%), GRA (103/µL), Lymph (103/µL; P=0.005) and MCV were significantly affected by I drenching. There was also a significant effect of I drench on enzyme parameters; alanine transaminase (ALT), alkaline phosphatase (ALP), aspartate transaminase (AST) and creatinine kinase (CK) of goats. In conclusions, I drenching had an impact on the most of the blood hematology and enzymes parameter of the goat throughout the time of the study
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REFERENCES
Aghwan, Z.A., Sazili, A.Q., Alimon, A.R., Goh, Y.M. and Hilmi, M., 2013. Blood haematology, serum thyroid hormones and glutathione peroxidase status in Kacang goats fed inorganic iodine and selenium supplemented diets. Asian-Australasian Journal of Animal Sciences, 26(11), p.1577.
Arain, M., Kamboh, A.A. and Arshed, M.J., 2021. Effects of selenium supplementation on hematological profile, gut microflora composition, in vitro biofilm formation assay and serum IgG concentration in goats. Pakistan Journal of Zoology, pp.1-8.
Ares, S., Quero, J. and de Escobar, G.M., 2008, December. Iodine balance, iatrogenic excess, and thyroid dysfunction in premature newborns. In Seminars in perinatology (Vol. 32, No. 6, pp. 407-412). WB Saunders.
Arfuso, F., Fazio, F., Rizzo, M., Marafioti, S., Zanghì, E. and Piccione, G., 2016. Factors affecting the hematological parameters in different goat breeds from Italy. Annals of Animal Science, 16(3), p.743.
Cepeda-Palacios, R., Fuente-Gómez, M.G., Ramírez-Orduña, J.M., García-Álvarez, A., Llinas-Cervantes, X. and Angulo, C., 2018. Effects of pregnancy and post-kidding stages on haematochemical parameters in cross-bred goats. Journal of Applied Animal Research, 46(1), pp.269-273.
De Benoist, B., McLean, E., Andersson, M. and Rogers, L., 2008. Iodine deficiency in 2007: global progress since 2003. Food and nutrition bulletin, 29(3), pp.195-202.
Djuricic, D., Dobranic, T., Grizelj, J., Gracner, D., Harapin, I., Stanin, D., Folnozic, I., Getz, I., Cvitkovic, D. and Samardzija, M., 2011. Concentrations of total proteins and albumins, and AST, AP, CK and GGT activities in the blood serum Boer and Saanen goats during puerperium. Reproduction in domestic animals, 46(4), pp.674-677.
Dušová, H., Trávníček, J., Peksa, Z., Šimák-Líbalová, K., Šimková, A., Falta, D. and Švejdová, K., 2014. The influence of high iodine intake on chosen blood parameters of sheep. Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 62, p.8.
Fortagne, M. and Schäfer, M., 1989. Hematologic parameters of Probstheidaer pigmy goats in relation to pregnancy and lactation. Archiv fur Experimentelle Veterinarmedizin, 43(2), pp.223-230.
He, Z.X., Sun, Z.H., Tan, Z.L., Tang, S.X., Zhou, C.S., Han, X.F., Wang, M., Wu, D.Q., Kang, J.H. and Beauchemin, K.A., 2012. Effects of maternal protein or energy restriction during late gestation on antioxidant status of plasma and immune tissues in postnatal goats. Journal of Animal Science, 90(12), pp.4319-4326.
Juma, K.H. and Alkass, I.E., 2005. Native goats of Iraq: A review. Dirasat, Agric. Sci, 32(2), pp.180-188.
Kadum, N.B. and Luaibi, O.K., 2017. Clinical study hypothyroidism in goats and treatment by iodine compounds. Journal of entomology and Zoology Studies.
Khalid, S.E., 2015. Assessment of Serum Creatine Kinase, Aspartate aminotransferase and Alanine aminotransferase Activity Levels in Sudanese Patients with Hypothyroidism in Khartoum State (Doctoral dissertation, Sudan University of Science and Technology).
Kim, Y.Y. and Mahan, D.C., 2001. Comparative effects of high dietary levels of organic and inorganic selenium on selenium toxicity of growing-finishing pigs. Journal of Animal Science, 79(4), pp.942-948.
Manohar, M., Davis, J., Vijayakumar, K., Kumar, V. and Rajan, S.K., 2021. Haemato-biochemical alterations in caprine theileriosis. Platelets (x103/µl), 401(37.757), pp.579-5.
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Meschy, F., 2000. Recent progress in the assessment of mineral requirements of goats. Livestock Production Science, 64(1), pp.9-14.
National Research Council (NRC) 2007. Nutrient requirements of small ruminants: Sheep, Goats, Cervids, and New World Camelids, 6th edition, pp. 129–131. National Academy Press, Washington, DC, USA.
Nudda, A., Battacone, G., Decandia, M., Acciaro, M., Aghini-Lombardi, F., Frigeri, M. and Pulina, G., 2009. The effect of dietary iodine supplementation in dairy goats on milk production traits and milk iodine content. Journal of dairy science, 92(10), pp.5133-5138.
Nyblom, H., Berggren, U., Balldin, J. and Olsson, R., 2004. High AST/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking. Alcohol and alcoholism, 39(4), pp.336-339.
Omar, M.S. and Desouky, D.E.S., 2015. Environmental, urinary iodine status and prevalence of goitre among schoolchildren in a high altitude area of Saudi Arabia. Pakistan journal of medical sciences, 31(2), p.414.
Oramari, R.A., Bamerny, A.O. and Zebari, H.M., 2014. Factors affecting some hematology and serum biochemical parameters in three indigenous sheep breeds. Advances in Life Science and Technology, 21, pp.56-63.
Panadi, M., Mohamed, W.Z., Rusli, N.D. and Mat, K., 2018. Effects of medicated and non-medicated multi-nutrient block supplementation on gastrointestinal parasite infestation and blood hematological parameters of lactating Saanen goats. Sains Malaysiana, 47(7), pp.1447-1453.
Pattanaik, A.K., Khan, S.A. and Goswami, T.K., 2011. Iodine supplementation to a diet containing Leucaena leucocephala leaf meal: consequences on nutrient metabolism, clinical chemistry and immunity of goats. Animal Production Science, 51(6), pp.541-548.
Peschke, E., Peschke, D., Rúzsás, C. and Helwin, H., 1988. Creatine kinase in hypo-and hyperthyroid rats under consideration of the circadian oscillations. Experimental and Clinical Endocrinology & Diabetes, 92(04), pp.91-96.
Potter, B.J., Mano, M.T., Belling, G.B., McIntosh, G.H., Hua, C., Cragg, B.G., Marshall, J., Wellby, M.L. and Hetzel, B.S., 1982. Retarded fetal brain development resulting from severe dietary iodine deficiency in sheep. Neuropathology and Applied Neurobiology, 8(4), pp.303-313.
Rajendran, D., Pattanaik, A.K., Khan, S.A. and Bedi, S.P.S., 2001. Iodine supplementation of Leucaena leucocephala diet for goats. II. Effects on blood metabolites and thyroid hormones. Asian-Australasian Journal of Animal Sciences, 14(6), pp.791-796.
Sandabe, U. K., D. Yahi (2000): Effect of pregnancy on some haematological parameters in Sahel goats. Annals of Borno 27, 326-330.
Sarker, D., Akter, M.A., Rahman, M.S., Yesmin, N. and Alam, M.M., 2020. Clinicopathological consequences of urinary retention due to urolithiasis in indigenous goats. PSM Veterinary Research, 5(2), pp.28-37.
Shi, L., Ren, Y., Zhang, C., Yue, W. and Lei, F., 2017. Effects of maternal dietary selenium (Se-enriched yeast) on growth performance, antioxidant status and haemato-biochemical parameters of their male kids in Taihang black goats. Animal Feed Science and Technology, 231, pp.67-75.
Shi, L., Ren, Y., Zhang, C., Yue, W. and Lei, F., 2018. Effects of organic selenium (Se-enriched yeast) supplementation in gestation diet on antioxidant status, hormone profile and haemato-biochemical parameters in Taihang Black Goats. Animal Feed Science and Technology, 238, pp.57-65.
Smith, D.P., 1976. The relationship between serum creatine kinase and thyroid hormones: in vivo and in vitro studies. Clinica Chimica Acta, 68(3), pp.333-338.
Sokkar, S.M., Soror, A.H., Ahmed, Y.F., Ezzo, O.H. and Hamouda, M.A., 2000. Pathological and biochemical studies on experimental hypothyroidism in growing lambs. Journal of Veterinary Medicine, Series B, 47(9), pp.641-652.
Tay, S. P., Cheong, S. K., Hamidah, N. H., Ainoon O., 1998. Flow cytometric analysis of intracellular myeloperoxidase distinguishes lymphocytes, monocytes and granulocytes. Malays J Pathol, 20, pp91–94.
Waziri, M.A., Ribadu, A.Y. and Sivachelvan, N., 2010. Changes in the serum proteins, hematological and some serum biochemical profiles in the gestation period in the Sahel goats. Vet. arhiv, 80(2), pp.215-224.
Zebari, M.H., Buti, E.T.S. and Hamo, R.A.H., 2013. Some blood biochemical parameters of meriz does during different physiological status. Sovetskii Vrachebnyi Sbornik, 18, pp.190-194.
Aghwan, Z.A., Sazili, A.Q., Alimon, A.R., Goh, Y.M. and Hilmi, M., 2013. Blood haematology, serum thyroid hormones and glutathione peroxidase status in Kacang goats fed inorganic iodine and selenium supplemented diets. Asian-Australasian Journal of Animal Sciences, 26(11), p.1577.
Arain, M., Kamboh, A.A. and Arshed, M.J., 2021. Effects of selenium supplementation on hematological profile, gut microflora composition, in vitro biofilm formation assay and serum IgG concentration in goats. Pakistan Journal of Zoology, pp.1-8.
Ares, S., Quero, J. and de Escobar, G.M., 2008, December. Iodine balance, iatrogenic excess, and thyroid dysfunction in premature newborns. In Seminars in perinatology (Vol. 32, No. 6, pp. 407-412). WB Saunders.
Arfuso, F., Fazio, F., Rizzo, M., Marafioti, S., Zanghì, E. and Piccione, G., 2016. Factors affecting the hematological parameters in different goat breeds from Italy. Annals of Animal Science, 16(3), p.743.
Cepeda-Palacios, R., Fuente-Gómez, M.G., Ramírez-Orduña, J.M., García-Álvarez, A., Llinas-Cervantes, X. and Angulo, C., 2018. Effects of pregnancy and post-kidding stages on haematochemical parameters in cross-bred goats. Journal of Applied Animal Research, 46(1), pp.269-273.
De Benoist, B., McLean, E., Andersson, M. and Rogers, L., 2008. Iodine deficiency in 2007: global progress since 2003. Food and nutrition bulletin, 29(3), pp.195-202.
Djuricic, D., Dobranic, T., Grizelj, J., Gracner, D., Harapin, I., Stanin, D., Folnozic, I., Getz, I., Cvitkovic, D. and Samardzija, M., 2011. Concentrations of total proteins and albumins, and AST, AP, CK and GGT activities in the blood serum Boer and Saanen goats during puerperium. Reproduction in domestic animals, 46(4), pp.674-677.
Dušová, H., Trávníček, J., Peksa, Z., Šimák-Líbalová, K., Šimková, A., Falta, D. and Švejdová, K., 2014. The influence of high iodine intake on chosen blood parameters of sheep. Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 62, p.8.
Fortagne, M. and Schäfer, M., 1989. Hematologic parameters of Probstheidaer pigmy goats in relation to pregnancy and lactation. Archiv fur Experimentelle Veterinarmedizin, 43(2), pp.223-230.
He, Z.X., Sun, Z.H., Tan, Z.L., Tang, S.X., Zhou, C.S., Han, X.F., Wang, M., Wu, D.Q., Kang, J.H. and Beauchemin, K.A., 2012. Effects of maternal protein or energy restriction during late gestation on antioxidant status of plasma and immune tissues in postnatal goats. Journal of Animal Science, 90(12), pp.4319-4326.
Juma, K.H. and Alkass, I.E., 2005. Native goats of Iraq: A review. Dirasat, Agric. Sci, 32(2), pp.180-188.
Kadum, N.B. and Luaibi, O.K., 2017. Clinical study hypothyroidism in goats and treatment by iodine compounds. Journal of entomology and Zoology Studies.
Khalid, S.E., 2015. Assessment of Serum Creatine Kinase, Aspartate aminotransferase and Alanine aminotransferase Activity Levels in Sudanese Patients with Hypothyroidism in Khartoum State (Doctoral dissertation, Sudan University of Science and Technology).
Kim, Y.Y. and Mahan, D.C., 2001. Comparative effects of high dietary levels of organic and inorganic selenium on selenium toxicity of growing-finishing pigs. Journal of Animal Science, 79(4), pp.942-948.
Manohar, M., Davis, J., Vijayakumar, K., Kumar, V. and Rajan, S.K., 2021. Haemato-biochemical alterations in caprine theileriosis. Platelets (x103/µl), 401(37.757), pp.579-5.
McClure, S.J., 2008. How minerals may influence the development and expression of immunity to endoparasites in livestock. Parasite immunology, 30(2), pp.89-100.
Meschy, F., 2000. Recent progress in the assessment of mineral requirements of goats. Livestock Production Science, 64(1), pp.9-14.
National Research Council (NRC) 2007. Nutrient requirements of small ruminants: Sheep, Goats, Cervids, and New World Camelids, 6th edition, pp. 129–131. National Academy Press, Washington, DC, USA.
Nudda, A., Battacone, G., Decandia, M., Acciaro, M., Aghini-Lombardi, F., Frigeri, M. and Pulina, G., 2009. The effect of dietary iodine supplementation in dairy goats on milk production traits and milk iodine content. Journal of dairy science, 92(10), pp.5133-5138.
Nyblom, H., Berggren, U., Balldin, J. and Olsson, R., 2004. High AST/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking. Alcohol and alcoholism, 39(4), pp.336-339.
Omar, M.S. and Desouky, D.E.S., 2015. Environmental, urinary iodine status and prevalence of goitre among schoolchildren in a high altitude area of Saudi Arabia. Pakistan journal of medical sciences, 31(2), p.414.
Oramari, R.A., Bamerny, A.O. and Zebari, H.M., 2014. Factors affecting some hematology and serum biochemical parameters in three indigenous sheep breeds. Advances in Life Science and Technology, 21, pp.56-63.
Panadi, M., Mohamed, W.Z., Rusli, N.D. and Mat, K., 2018. Effects of medicated and non-medicated multi-nutrient block supplementation on gastrointestinal parasite infestation and blood hematological parameters of lactating Saanen goats. Sains Malaysiana, 47(7), pp.1447-1453.
Pattanaik, A.K., Khan, S.A. and Goswami, T.K., 2011. Iodine supplementation to a diet containing Leucaena leucocephala leaf meal: consequences on nutrient metabolism, clinical chemistry and immunity of goats. Animal Production Science, 51(6), pp.541-548.
Peschke, E., Peschke, D., Rúzsás, C. and Helwin, H., 1988. Creatine kinase in hypo-and hyperthyroid rats under consideration of the circadian oscillations. Experimental and Clinical Endocrinology & Diabetes, 92(04), pp.91-96.
Potter, B.J., Mano, M.T., Belling, G.B., McIntosh, G.H., Hua, C., Cragg, B.G., Marshall, J., Wellby, M.L. and Hetzel, B.S., 1982. Retarded fetal brain development resulting from severe dietary iodine deficiency in sheep. Neuropathology and Applied Neurobiology, 8(4), pp.303-313.
Rajendran, D., Pattanaik, A.K., Khan, S.A. and Bedi, S.P.S., 2001. Iodine supplementation of Leucaena leucocephala diet for goats. II. Effects on blood metabolites and thyroid hormones. Asian-Australasian Journal of Animal Sciences, 14(6), pp.791-796.
Sandabe, U. K., D. Yahi (2000): Effect of pregnancy on some haematological parameters in Sahel goats. Annals of Borno 27, 326-330.
Sarker, D., Akter, M.A., Rahman, M.S., Yesmin, N. and Alam, M.M., 2020. Clinicopathological consequences of urinary retention due to urolithiasis in indigenous goats. PSM Veterinary Research, 5(2), pp.28-37.
Shi, L., Ren, Y., Zhang, C., Yue, W. and Lei, F., 2017. Effects of maternal dietary selenium (Se-enriched yeast) on growth performance, antioxidant status and haemato-biochemical parameters of their male kids in Taihang black goats. Animal Feed Science and Technology, 231, pp.67-75.
Shi, L., Ren, Y., Zhang, C., Yue, W. and Lei, F., 2018. Effects of organic selenium (Se-enriched yeast) supplementation in gestation diet on antioxidant status, hormone profile and haemato-biochemical parameters in Taihang Black Goats. Animal Feed Science and Technology, 238, pp.57-65.
Smith, D.P., 1976. The relationship between serum creatine kinase and thyroid hormones: in vivo and in vitro studies. Clinica Chimica Acta, 68(3), pp.333-338.
Sokkar, S.M., Soror, A.H., Ahmed, Y.F., Ezzo, O.H. and Hamouda, M.A., 2000. Pathological and biochemical studies on experimental hypothyroidism in growing lambs. Journal of Veterinary Medicine, Series B, 47(9), pp.641-652.
Tay, S. P., Cheong, S. K., Hamidah, N. H., Ainoon O., 1998. Flow cytometric analysis of intracellular myeloperoxidase distinguishes lymphocytes, monocytes and granulocytes. Malays J Pathol, 20, pp91–94.
Waziri, M.A., Ribadu, A.Y. and Sivachelvan, N., 2010. Changes in the serum proteins, hematological and some serum biochemical profiles in the gestation period in the Sahel goats. Vet. arhiv, 80(2), pp.215-224.
Zebari, M.H., Buti, E.T.S. and Hamo, R.A.H., 2013. Some blood biochemical parameters of meriz does during different physiological status. Sovetskii Vrachebnyi Sbornik, 18, pp.190-194.
Published
2022-10-25
How to Cite
SALIH , H. S., & ZEBARI, H. M. H. (2022). EFFECT OF IODINE DOSES ON HEMATOLOGICAL AND ENZYMES PARAMETERS OF BLACK GOATS DURING LATE PREGNANCY PERIOD . Journal of Duhok University, 25(2), 56-64. https://doi.org/10.26682/ajuod.2022.25.2.6
Section
Agriculture and Veterinary Science
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