NEPHRECTOMY. A CLINICOPATHOLOGICAL STUDY

ABDULGHAFOOR S. ABDULKAREEM; BASHAR A. HASSAWI

doi:10.26682/10.26682/sjuod.2018.21.1.8

ABDULGHAFOOR S. ABDULKAREEM Dept. of Surgery. College of Medicine, University of Duhok, Kurdistan Region-Iraq
BASHAR A. HASSAWI Dept. of Anatomy. College of Medicine, University of Duhok, Kurdistan Region-Iraq

DOI: https://doi.org/10.26682/10.26682/sjuod.2018.21.1.8

Keywords: Nephrectomy, Renal tumor, clinicopathological

Abstract

Background: To provide the urologist with the proper histopathological diagnosis of nephrectomy specimens, to correlate the compatibilty of clinical diagnosis and indications of nephrectomy with histopathological results and to see the relative frequency of each type and its specific pathologic characters. The study was conducted at Azadi teaching hospital and in the department of pathology, college of medicine, university of Duhok during a period from (Nov 2012 – Nov 2014). A total 161 nephrectomy specimens were examined grossly. Representative blocks were taken for histopathological examination. 76 patients (47.2%) of the patients were males, (85) 52.8% were females, with male: female ratio of 1:1.08. The mean age was 35.6 years. The histological examinations revealed in descending order 62.65% were inflammatory conditions (including chronic pyelonephritis, xanthogranulomatous pyelonephritis and tuberculous pyelonephritis). Adult type malignant conditions were found in 26% of the total cases (including renal cell carcinoma and transitional cell carcinoma). Only one case was lymphoma and other metastatic carcinoma. 9.8 % were cystic lesions of the kidney, 4.96 % were pediatric tumors (including nephroblastoma only), 2.48% was angiomyolipoma. The study concludes a wide range of renal pathology in this locality, histopathological examination for every nephrectomy specimen is the corner stone for a clinico-morphological correlation and proper management. The chronic pyelonephritis is the most and frequent pathologic indication for nephrectomy irrespective of age or sex. Xanthogranulomatous pyelonephritis is seen in age below 25 years and was usually associated with nephrolithiasis. Renal cell carcinoma is the most common kidney cancer in adults affects mainly males followed by transitional cell carcinoma and Nephroblastoma which is the main type of malignant tumors of the kidney in children. Secondary in the kidney, SCC and lymphoma are rare tumors.

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