EXTRACTIVE CLOUD POINT SPECTROPHOTOMETRIC DETERMINATION OF MESALAZINE USING BRILLIANT GREEN DYE
Keywords:
Ion-pair, Cloud point, Brilliant green, Mesalazine
Abstract
A simple and accurate cloud point-spectrophotometric method for determination of Mesalazine (MEZ) in pure form and pharmaceutical formulations is proposed. The procedure is based on the reaction of Mesalazine with brilliant green dye (BG) forming a pale-yellow ion-pair complex after extracting with Triton X-114 and measured at 361 nm. The experimental conditions for the phase separation were optimized. Beer’s law was obeyed in the range 0.3-3.5 µg mL-1 with molar absorptivity of 3.914×104 L.mol-1.cm-1, average recovery % of 100.82 and average relative standard deviation (RSD) is 0.87. The method was applied successfully for determination of MEZ in its pharmaceutical formulations
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References
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Fatima Altayib Alasha Abdalla and Abdalla Ahmed Elbashir. (2014). Development and Validation of Spectrophotometric Methods for the Determination of Mesalazine in Pharmaceutical Formulation. Medicinal Chemistry, Volume 4(3), 361–366.
Gatkal, S. H., Mhatre, P. R., Chopade, V. V., & Choudhari, P. D. (2013). Development and validation of stability indicating HPLC assay method for determination of mesalamine in bulk drug and tablet formulation. International Journal of Pharmaceutical Sciences Review and Research, 20(1), 200–204.
Gurupadayya, B. (2011). Spectrophotometric Determination of Mesalamine by Pdac and Nqs Reagents in Bulk and Tablet Dosage Form. Journal of Pharmacy Research, 4(1), 39–41. http://jprsolutions.info
Kanubhai, T. R., Mukesh, P. and Amit, K. (2011). Determination of Mesalamine Related Impurities from Drug Product by Reversed Phase Validated UPLC Method. E-Journal of Chemistry, 1(8), 131–148.
Liang, P., & Yang, J. (2010). Cloud Point Ex- traction preconcentration and spectropho- tometric determination of copper in food and water samples using amino acid as the complexing Agent. J. Food Com- pos. Anal., 23(1): 95-99.
Madhavi, V., Panchakshari, V., Prathyusha, T. N., & Sekaran, C. B. (2011). Spectrophotometric determination of mesalazine in bulk and tablet dosage forms based on diazocoupling reaction with resorcinol. International Journal of Pharmaceutical Sciences Review and Research, 11(1), 105–109.
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Teradale, A. B., Lamani, S. D., Ganesh, P. S., Swamyc, B. E. K., & Dasa, S. N. (2017). CTAB immobilized carbon paste electrode for the determination of mesalazine: A cyclic voltammetric method Amit. Sensing and Bio-Sensing Research Journal, 15, 53–59.
Theia’a N. Al-Sabha and Nagham N. Habeb. (2018). Simultaneous Spectrophotometric Determination of Mesalasine and Isoniazid Using H-Point Standard Addition Method via Schiff’s Base Formation Reaction. Iraqi National Journal of Chemistry, 18(2), 73–84.
Trung Dung, N., Thi Lan Anh, N., Thi Oanh, D., & Hoang Dung, N. (2016). Development of spectrophotometric method for determination of mesalazine in pharmaceutical preparation. Vietnam Journal of Chemistry, 54(4), 509–514. http://www.vjst.net/index.php/vjchem/article/view/0866-7144.2016-00356
Watanabe, H., & Tanaka, H. (1978). A Non- ionic Surfactant as a New Solvent for Liquid-liquid Extraction of Zinc(II) with 1-(2-pyridylazo)-2-naphthol Talanta, 25:585-589.
Wiersma, H., Escher, J. C., Dilger, K., Trenk, D., Benninga, M. A., van Boxtel, C. J., & Taminiau, J. (2004). Pharmacokinetics of mesalazine pellets in children with inflammatory bowel disease. Inflammatory Bowel Diseases, 10(5), 626–631. https://doi.org/10.1097/00054725-200409000-00019
Zain, N., Abu Bakar, N., Mohamad, S., & Saleh, N. M. (2014). optimization of a greener method for removal phenol species by Cloud Point Extraction and Spectrophotometry. Spectrochim Acta A, 118: 1121-1128.
Al-Sabha, T. N. and Habeeb, N. N. (2015). Spectrophotometric determination of Mesalazine using sodium nitroprusside as chromogenic reagent Determination of Drugs Via charge transfer complexes View project Ion-pair complex formation View project Spectrophotometric determination of mesalamine by so. In Eur. Chem. Bull (Vol. 4, Issue 8). https://www.researchgate.net/publication/330324624
Al-Zakaria, S. A. (2019). Spectrophotometric Determination of Mesalazine. Raf. J. Sci., 28(2), 127–134.
Ahmida , N. H.S., ESMAEL, M. A., EL-ENANY E. A. W. and Belal, F., (2009). Difference Spectrophotometric Method for the Determination of Metronidazole in Tablets, Asian Journal of Chemistry 21, (1), 755-762
Chandra, B. S., Bhogela, S. S., Shaik, M., Vadlamudi, C. S., Chappa, M., & Maddirala, N. S. (2011). Simple and sensitive spectrophotometric methods for the analysis of mesalamine in bulk and tablet dosage forms. In Quimica Nova (Vol. 34, Issue 6, pp. 1068–1073). https://doi.org/10.1590/S0100-40422011000600026
Desai, S. A., & Kale, P. R. N. (2019). Method Development and Validation of Mesalamine in Pharmaceutical Dosage Form: a Review. International Journal of Pharmaceutical and Biological Science Archive, 7(3), 105–108. https://doi.org/10.32553/ijpba.v7i3.130
Elbashir, A. A., Abdalla, F. A. A., & Aboul-Enein, H. Y. (2015). Supramolecular interaction of 18-crown-6 ether with mesalazine and spectrofluorimetric determination of mesalazine in pharmaceutical formulations. In Luminescence (Vol. 30, Issue 8, pp. 1250–1256). https://doi.org/10.1002/bio.2888
Enam A. Hamdoon. (2018). Indirect Spectrophotometric Determination of Mesalazine via Chromate-1,5-Diphenyl carbazide Complex. In Raf. J. Sci. (Vol. 27, Issue 2). https://rsci.mosuljournals.com/article_145392.html
Fatima Altayib Alasha Abdalla and Abdalla Ahmed Elbashir. (2014). Development and Validation of Spectrophotometric Methods for the Determination of Mesalazine in Pharmaceutical Formulation. Medicinal Chemistry, Volume 4(3), 361–366.
Gatkal, S. H., Mhatre, P. R., Chopade, V. V., & Choudhari, P. D. (2013). Development and validation of stability indicating HPLC assay method for determination of mesalamine in bulk drug and tablet formulation. International Journal of Pharmaceutical Sciences Review and Research, 20(1), 200–204.
Gurupadayya, B. (2011). Spectrophotometric Determination of Mesalamine by Pdac and Nqs Reagents in Bulk and Tablet Dosage Form. Journal of Pharmacy Research, 4(1), 39–41. http://jprsolutions.info
Kanubhai, T. R., Mukesh, P. and Amit, K. (2011). Determination of Mesalamine Related Impurities from Drug Product by Reversed Phase Validated UPLC Method. E-Journal of Chemistry, 1(8), 131–148.
Liang, P., & Yang, J. (2010). Cloud Point Ex- traction preconcentration and spectropho- tometric determination of copper in food and water samples using amino acid as the complexing Agent. J. Food Com- pos. Anal., 23(1): 95-99.
Madhavi, V., Panchakshari, V., Prathyusha, T. N., & Sekaran, C. B. (2011). Spectrophotometric determination of mesalazine in bulk and tablet dosage forms based on diazocoupling reaction with resorcinol. International Journal of Pharmaceutical Sciences Review and Research, 11(1), 105–109.
Mohammed S. Al-Enizzi, Theia’a N. Al-Sabha, T. S. A.-G. (2012). Use of Charge Transfer Complex Formation Reaction in Spectrophotometric Microdetermination of Some Drugs Mohammed. Jordan Journal of Chemistry, 7(1), 87–102.
Shehab1, A. A., & Muhammed2, D. H. (2020). Sys Rev Pharm. Sys Rev Pharm, 922–929.
Singh, R. K., Patel, P. S., Gupta, P., & Park, B. (2010). IJPSR (2010), Vol. 1, Issue 3 (Research Article). 1(3), 44–49.
Teradale, A. B., Lamani, S. D., Ganesh, P. S., Swamyc, B. E. K., & Dasa, S. N. (2017). CTAB immobilized carbon paste electrode for the determination of mesalazine: A cyclic voltammetric method Amit. Sensing and Bio-Sensing Research Journal, 15, 53–59.
Theia’a N. Al-Sabha and Nagham N. Habeb. (2018). Simultaneous Spectrophotometric Determination of Mesalasine and Isoniazid Using H-Point Standard Addition Method via Schiff’s Base Formation Reaction. Iraqi National Journal of Chemistry, 18(2), 73–84.
Trung Dung, N., Thi Lan Anh, N., Thi Oanh, D., & Hoang Dung, N. (2016). Development of spectrophotometric method for determination of mesalazine in pharmaceutical preparation. Vietnam Journal of Chemistry, 54(4), 509–514. http://www.vjst.net/index.php/vjchem/article/view/0866-7144.2016-00356
Watanabe, H., & Tanaka, H. (1978). A Non- ionic Surfactant as a New Solvent for Liquid-liquid Extraction of Zinc(II) with 1-(2-pyridylazo)-2-naphthol Talanta, 25:585-589.
Wiersma, H., Escher, J. C., Dilger, K., Trenk, D., Benninga, M. A., van Boxtel, C. J., & Taminiau, J. (2004). Pharmacokinetics of mesalazine pellets in children with inflammatory bowel disease. Inflammatory Bowel Diseases, 10(5), 626–631. https://doi.org/10.1097/00054725-200409000-00019
Zain, N., Abu Bakar, N., Mohamad, S., & Saleh, N. M. (2014). optimization of a greener method for removal phenol species by Cloud Point Extraction and Spectrophotometry. Spectrochim Acta A, 118: 1121-1128.
Published
2023-05-04
How to Cite
JABAR, F. M., ISMAEL, S. O., & AL-SABHA, T. N. (2023). EXTRACTIVE CLOUD POINT SPECTROPHOTOMETRIC DETERMINATION OF MESALAZINE USING BRILLIANT GREEN DYE. Journal of Duhok University, 26(1), 61-71. https://doi.org/10.26682/sjuod.2023.26.1.7
Section
Pure and Engineering Sciences
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