LEVEL OF D-DIMER AND C- REACTIVE PROTEIN  AMONG COVID-19 PATIENTS IN RELATION TO DIFFERENT AGES AND GENDERS

SAKAR AHMAD  ABDULLAH; HAREM OTHMAN  SMAIL; ALAA AHMED  RAHIM; TANYA KAMIL  MUHAMAD; BANWAN  MAJID; BINAY  ROSTAM; NAZ  NAWROZ; SIVER  AWAT; DYARI  KAMAL

doi:10.26682/sjuod.2023.26.1.21

SAKAR AHMAD ABDULLAH Dept. of Medical Laboratory, College of health and medical technology, Sulaimani Polytechnic University, Kurdistan Region–Iraq
HAREM OTHMAN SMAIL Dept. of Biology, Faculty of Science and Health, Koya University, Kurdistan Region–Iraq
ALAA AHMED RAHIM Dept. of Medical Laboratory, College of health and medical technology, Sulaimani Polytechnic University, Kurdistan Region–Iraq
TANYA KAMIL MUHAMAD Dept. of Medical Laboratory, College of health and medical technology, Sulaimani Polytechnic University, Kurdistan Region–Iraq
BANWAN MAJID Dept. of Medical Laboratory, College of health and medical technology, Sulaimani Polytechnic University, Kurdistan Region–Iraq
BINAY ROSTAM Dept. of Medical Laboratory, College of health and medical technology, Sulaimani Polytechnic University, Kurdistan Region–Iraq
NAZ NAWROZ Dept. of Medical Laboratory, College of health and medical technology, Sulaimani Polytechnic University, Kurdistan Region–Iraq
SIVER AWAT Dept. of Medical Laboratory, College of health and medical technology, Sulaimani Polytechnic University, Kurdistan Region–Iraq
DYARI KAMAL Dept. of Medical Laboratory, College of health and medical technology, Sulaimani Polytechnic University, Kurdistan Region–Iraq

DOI: https://doi.org/10.26682/sjuod.2023.26.1.21

Keywords: D-dimer, inflammatory biomarkers, CRP, inflammatory thrombosis and age

Abstract

coronavirus disease of 2019 (COVID-19) is a new infectious disease spreading worldwide rapidly. COVID-19 has been associated with a risk of thrombosis, which an increase in the level of D-dimer can detect. D-dimer is a small fragment of protein present in the blood after blood clot degradation. This research aimed to evaluate the level of D-Dimer and C- reactive protein in COVID-19 patients and ascertain the relation of these markers with age and gender. From December 2020 to January 2021, patients with laboratory reports of Covid-19 were retrospectively enrolled in different hospitals and private laboratories. We collected 253 cases of the D-dimer test for different ages and genders and 204 cases of C- reactive protein test with D-dimer to detect the severity of the disease. An increased level of D-dimer of more than 0.5 mcg/ml was reported in 105 patients (41.5%). According to gender, 43.7% of males and 38.79% of females have elevated D-dimer levels. In patients with COVID-19, D-dimer levels greater than 0.5mcg/mL could accurately predict in-hospital morbidity and mortality. Therefore, D-dimer has been proposed as a possible early and effective marker for improved management of COVID-19 patients

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