PULMONARY FUNCTIONS AND ITS CORRELATION WITH SERUM IRON LEVELS IN WOMEN AT THE THIRD TRIMESTER OF PREGNANCY
Abstract
Background and Objectives: There is a series of physiological alterations that taken place during pregnancy as a result of gradual growth of the fetus. Among alterations that occur during pregnancy are changes in the lung volumes. In this study we aim to evaluate the pulmonary functions in pregnant women at the third trimester of pregnancy and to determine the correlation between pulmonary functions and serum iron levels.
Methods: Physical examination as well as case history and all requested information were taken by a questionnaire. Measurement of serum iron was done manually using commercial kit (Biolab, France). Pulmonary functions test was carried out using a computerized Spirometer device (ROME-Italy).
Results: FEV1, FVC and O2 saturation % showed a decrease in study group (untreated) but were not statistically significant (p = 0.31, 0.98 and 0.14) respectively. However, only FEV1/FVC displayed a statistically significant decline in study group compared to controls. Although there was an obvious positive correlation between serum iron and FEV1, FVC and FEV1/FVC, none of them showed a statistically significant correlation (r = 0.238, 0.493 and 0.969) respectively.
Conclusion: Decline in lung volumes is correlated (although not significant) with low serum iron in pregnant women at the third trimester.
Downloads
References
Van den Broek NR, Letsky EA. Etiology of anemia in pregnancy in south Malawi. Am J Clin Nutr. 2000;72:247S–56S.
Gomber S, Agarwal KN, Mahajan C, Agarwal N. Impact of daily versus weekly hematianic supplementation on anemia in pregnant women. Indian Pediatr. 2002;39:339–46.
Mcfee JC. Iron metabolism and iron deficiency during pregnancy. Clin Obstet Gynecol. 1997;22:799–808.
Dongmei Sun, Anne McLeod, Shital Gandhi, Ann Kinga Malinowski, Nadine Shehata. Anemia in Pregnancy: A Pragmatic Approach. Obstet Gynecol Surv. 2017; 72(12): 730–737.
Bondevik GT, Lie RT, Ulsteim M, Kvale G. Maternal hematological status and risk of low birth weight and preterm delivery in Nepal. Acta Obstet Gynaecol Scand. 2001;80:402–8.
Neeraj, Sodhi Candy, Pramod J, Singh J, Kaur V. Effect of advanced uncomplicated pregnancy on pulmonary function parameters of North Indian subjects. Indian J. Physiol Pharmacol. 2010 : 54 (1) : 69-72.
Shaikh RM, Deshpande DR, Ganeriwal SK, Reddy BV: Effect of pregnancy on vital capacity and FEV1%. J Obst Gynecol. 1983; 33 : 495-499.
K Jagadish Kumar, N Asha, D Srinivasa Murthy, MS Sujatha and VG Manjunath. Maternal Anemia in Various Trimesters and its Effect on Newborn Weight and Maturity: An Observational Study. Int J Prev Med. 2013; 4(2): 193–199.
Malik Goonewardene, Mishkat Shehata, Asma Hamad. Anaemia in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2012; 26(1): 3–24.
Steer PJ. Maternal Hemoglobin concentration and birth weight. Am J Clin Nutr. 2000; 71:1285–7.
Papamatheakis DG, Blood AB, Kim JH, Wilson SM. Antenatal hypoxia and pulmonary vascular function and remodeling. Curr Vasc Pharmacol. 2013;11(5):616–640.
Y.SHAILAJA and S.SRIKANTH. Lung function tests in different trimesters of pregnancy. Indian Journal of Basic and Applied Medical Research. 2013: Vol.-3, Issue-1, P.285-292
Siddiqui AH, Tauheed N, Ahmad A, Mohsin Z. Pulmonary function in advanced uncomplicated singleton and twin pregnancy. J Bras Pneumol. 2014; 40(3):244–249.
Sroczynski T, Gawlikowska-Sroka A, Dzieciolowska-Baran E, Poziomkowska-Gesicka I. Causes of respiratory ailments in pregnancy. Eur J Med Res. 2015; 2:189–192.
Bobrowski RA. Pulmonary physiology in pregnancy. Clin Obstet Gynecol. 2010, 53:285-300.
Girija Priyadarshini. Evaluation of Pulmonary Functions In Third Trimester Pregnant Odia Women and Its Correlation with Severity of Anaemia. IOSR Journal of Dental and Medical Sciences. 2014; (13): 100-104.
Pathak MS, Kurhade G.A., A longitudinal study of antenatal changes in lung function tests and importance of postpartum exerci ses in their recovery. Indian J. Physiol Pharmacol. 2003 : 47 (3) : 352-356.
B. M. Puranik, S. B. Kaore, G. A. Kurhade, S. D. Agrawal, S. A. Patwardhan, J. R. Kher. A longitudinal study of pulmonary function tests during pregnancy. Indian J Physiol Pharmacol. 2014; 38(2): 129–132.
L. Hirnle, L. Lysenko, H. Gerber, P. Lesnik, A. Baranowska, M. Rachwalik, J. Leszczyszyn, L. Strozecki. Respiratory function in pregnant women. Adv Exp Med Biol. 2013; 788: 153–160.
Gupta P, Pande J.N, Pulmonary and diaphragmatic functions in chronic severe nutritional anaemia. The National Medical Journal of India. 1989; 2 (6) : P – 266 – 268.
Singhal U, Saxena K. Effect of anaemia on respiratory and metabolic parameters during 3rd trimester of pregnancy. Indian J Physiol Pharmacol. 1987;31(2):130-135.
Dutt SN, Yeshwanth M, Raghuveer TS. Effect of iron deficiency anaemia on pulmonary function in children. Lung India. 1944 ;12(4):168-73.
Dash S, Nanda SS, Behera AK. Pulmonary functions in pregnancy complicated with anemia. Int J Res Med Sci. 2014;2:1431-7.
Ganeriwal SK, Deshpande DR, Reddy BV, Shaikh RM. Effect of pregnancy on pulmonary ventilation. J Obstet Gynecol India. 1984;36:639-41
It is the policy of the Journal of Duhok University to own the copyright of the technical contributions. It publishes and facilitates the appropriate re-utilize of the published materials by others. Photocopying is permitted with credit and referring to the source for individuals use.
Copyright © 2017. All Rights Reserved.
