SOFT PALATE SCHWANNOMA: A CASE REPORT
Keywords:
Schwannoma, soft palate, LED laser.
Abstract
Schwannoma (neurilemmoma) is one of the rare lesions that affect the oral mucosa. It is a benign lesion originated from Schwann cells which form myelin sheath of myelinated nerves. Most of the cases are asymptomatic, but in symptomatic cases, the signs and symptoms depend on its size and location. 25% of the cases of schwannoma occur in the head and neck but the intraoral cases form only 1% of the extracranial head and neck schwannoma. Most of the intraoral schwannoma occur in the tongue, but it can also affect other parts of oral cavity like palatal mucosa, floor of the mouth, cheeks, labial mucosa and jaws. In the following case report, a 28 years old female diagnosed with schwannoma in the soft palate which is extremely a rare case. The tumor was asymptomatic, slowly growing, round in shape, 5mm in diameter but the patient was obsessive from the mass. The lesion was excised by LED laser (epic x, Biolase) and sent immediately to histopathology. The laboratory report showed that the lesion was strongly positive to anti S100 protein. The patient after 10 months of follow up is well controlled and with no recurrence of the tumor
Downloads
Download data is not yet available.
References
Rajiv Joshi. Learning from eponyms: Jose Verocay and Verocay bodies, Antoni A and B areas, Nils Antoni and Schwannomas. Indian Dermatol Online J. 2012 Sep-Dec; 3(3): 215–219. doi: 10.4103/2229-5178.101826.
Nalini Aswath, T Manigandan, S Leena Sankari, and Lakshanika Yogesh. A rare case of palatal schwannoma with literature review. J Oral MaxillofacPathol.2019 Feb; 23(Suppl 1): 36–39. doi: 10.4103/jomfp.JOMFP_242_16.
Jakob Kavčič and Marko Božič. Schwannoma of the tongue. BMJ Case Rep. 2016; 2016: bcr2016215799. Published online 2016 Oct 10. doi: 10.1136/bcr-2016-215799.
Seema Kurup, Krishnakumar Thankappan, Nitin Krishnan, and Preeti P Nair. Intraoral schwannoma – a report of two cases. BMJ Case Rep. 2012; 2012: bcr1220115389. Published online 2012 Jul 27. doi: 10.1136/bcr.12.2011.5389.
Abdelkarim Rhanim, MD,∗Rachid El Zanati, MD, Mustapha Mahfoud, PhD, Mohammed Saleh Berrada, PhD, and Moradh El Yaacoubi. A rare cause of chronic sciatic pain: Schwannoma of the sciatic nerve. J Clin Orthop Trauma. 2013 Jun; 4(2): 89–92. Published online 2013 Apr 26. doi: 10.1016/j.jcot.2013.04.001
Alhanouf A. Alhedaithy, Anwaar M. Alsayed, Khalid A. Al-Sindi, and Waleed M. Janahi. Schwannoma originating in the soft palate: A case report. Int J Surg Case Rep. 2021 Jul; 84: 106108. Published online 2021 Jun 17. doi: 10.1016/j.ijscr.2021.106108
Ricardo Ramina, Maurício Coelho Neto, Kelly Cristina Bordignon, Tobias Mattei, Rogério Clemente, and Paulo Henrique Pires Aguiar.Treatment of Large and Giant Residual and Recurrent Vestibular Schwannomas. Skull Base. 2007 Mar; 17(2): 109–117. Prepublished online 2006 Nov 1. doi: 10.1055/s-2006-953510
XinweiLi,GuohuaZhong,XueyingXu,KunWang,YinxinZhu,XuchenQi,JunhuiLv,YirongWang,SenShao. Surgical strategies for peripheral nerve schwannoma based on the intraoperative neurophysiological monitoring. Laparoscopic, Endoscopic and Robotic Surgery. Volume 2, Issue 3, September 2019, Pages 65-69.
Carlos Moreno-García,María Asunción Pons-García, Raúl González-García, and Florencio Monje-Gil. J Maxillofac Oral Surg.Schwannoma of Tongue. 2014 Jun; 13(2): 217–221. Published online 2011 Mar 25. doi: 10.1007/s12663-010-0101-0
Tamgadge Avinash, Tamgadge Sandhya, ShashibhushanDodal, Mayura Chande, and Treville Pereira. Recurrent Ancient Intraosseous Neurilemmoma of Maxilla: A Rare Case Report. Iran J Pathol. 2016 Spring; 11(2): 176–180.
Ankur Majumder, Arvind Ahuja, DS Chauhan, Purnima Paliwal, and Minakshi Bhardwaj. A clinicopathological study of peripheral schwannomas. Med Pharm Rep. 2021 Apr; 94(2): 191–196. Published online 2021 Apr 29. doi: 10.15386/mpr-1708.
José Antonio Galbiatti, Gabriel Rodrigues dos Santos Milhomens, Lara Giovanetti Bertozzo, Letícia Escames, Pedro de Alcântara Milhomens Neto, and Marilia Gabriela Palacio Galbiatti. Retrospective Analysis of 20 Patients Affected by Schwannomas in the Upper and Lower Limbs. Rev Bras Ortop (Sao Paulo). 2020 Oct; 55(5): 629–636. Published online 2020 Apr 6. doi: 10.1055/s-0040-1702962.
Swati Parhar, Harkanwal Preet Singh, Amit Nayyar, and Adesh S Manchanda. Intra-Oral Schwannoma- A Case Report. J Clin Diagn Res. 2014 Mar; 8(3): 264–265. Published online 2014 Mar 15. doi: 10.7860/JCDR/2014/7466.4181
M. Panduranga Kamath, Hema Kini,S.Vijendra Shenoy, D. Deviprasad, Nidhin Prakash, Radha Pai. Schwannoma of the base of tongue – A rare presentation. Egyptian Journal of Ear, Nose, Throat and Allied Sciences (2014) 15, 61–64
Williams H.K., Cannell H., Silvester K., Williams D.M. Neurilemmoma of the head and neck. Br. J. Oral Maxillofac. Surg. 1993; 31:32–35.
9. Lucas R.B. Pathology of Tumors of the Oral Tissue. 1984. New York, NY: Churchill Livingstone.
Wright B.A., Jackson D. Neural tumors of the oral cavity: a review of the spectrum of benign and malignant oral tumors of the oral cavity and jaws. Oral Surg. Oral Med. Oral Pathol. 1980;49: 509–522.
Shannon Coy, Rumana Rashid, Anat Stemmer-Rachamimov, and Sandro Santagata. An update on the CNS manifestations of neurofibromatosis type 2. Acta Neuropathol. 2020; 139(4): 643–665. Published online 2019 Jun 4. doi: 10.1007/s00401-019-02029-5.
Gainza-Cirauqui M.L., Eguía-Del Valle A., Martínez-Conde R., Coca-Meneses J.C., Aguirre-Urizar J.M. Ancient schwanomma of the hard palate. An uncommon case report and review. J Clin Exp Dent. 2013;5: e62–e65.
Jacob Pe’er. Pathology of eyelid tumors. Indian J Ophthalmol. 2016 Mar; 64(3): 177–190. doi: 10.4103/0301-4738.181752.
Abhishek Jaiswal, Asit Ranjan Mridha, Devajit Nath, Ashu Seith Bhalla, and Alok Thakkar. Intraparotid facial nerve schwannoma: A case report. World J Clin Cases. 2015 Mar 16; 3(3): 322–326. Published online 2015 Mar 16. doi: 10.12998/wjcc.v3.i3.322
Kun Z., Qi D.Y., Zhang K.H. A comparison between the clinical behavior of neurilemmomas in the neck and oral and maxillofacial region. J. Oral Maxillofac. Surg. 1993;51: 769–771.
F.J. Wippold, II, M. Lubner, R.J. Perrin, M. Lämmle, and A. Perry. Neuropathology for the Neuroradiologist: Antoni A and Antoni B Tissue Patterns. AJNR Am J Neuroradiol. 2007 Oct; 28(9): 1633–1638. doi: 10.3174/ajnr.A0682.
S Simonetti, C Serrano, J Hernández-Losa, S Bagué, R Orellana, C Valverde, M E Lleonart, M Aizpurua, J Carles, S Ramón y Cajal, C Romagosa. Schwannomas, benign tumors with a senescent phenotype. HistolHistopathol. 2014 Jun;29(6):721-30. doi: 10.14670/HH-29.721. Epub 2013 Nov 12.
Rodriguez F.J. Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems. Acta Neuropathol. 2012;123: 295–319.
Bansal R., Trivedi P., Patel S. Schwannoma of the tongue. Oral Oncol. Extra. 2005; 41:15–17.
Nalini Aswath, T Manigandan, S Leena Sankari, and Lakshanika Yogesh. A rare case of palatal schwannoma with literature review. J Oral MaxillofacPathol.2019 Feb; 23(Suppl 1): 36–39. doi: 10.4103/jomfp.JOMFP_242_16.
Jakob Kavčič and Marko Božič. Schwannoma of the tongue. BMJ Case Rep. 2016; 2016: bcr2016215799. Published online 2016 Oct 10. doi: 10.1136/bcr-2016-215799.
Seema Kurup, Krishnakumar Thankappan, Nitin Krishnan, and Preeti P Nair. Intraoral schwannoma – a report of two cases. BMJ Case Rep. 2012; 2012: bcr1220115389. Published online 2012 Jul 27. doi: 10.1136/bcr.12.2011.5389.
Abdelkarim Rhanim, MD,∗Rachid El Zanati, MD, Mustapha Mahfoud, PhD, Mohammed Saleh Berrada, PhD, and Moradh El Yaacoubi. A rare cause of chronic sciatic pain: Schwannoma of the sciatic nerve. J Clin Orthop Trauma. 2013 Jun; 4(2): 89–92. Published online 2013 Apr 26. doi: 10.1016/j.jcot.2013.04.001
Alhanouf A. Alhedaithy, Anwaar M. Alsayed, Khalid A. Al-Sindi, and Waleed M. Janahi. Schwannoma originating in the soft palate: A case report. Int J Surg Case Rep. 2021 Jul; 84: 106108. Published online 2021 Jun 17. doi: 10.1016/j.ijscr.2021.106108
Ricardo Ramina, Maurício Coelho Neto, Kelly Cristina Bordignon, Tobias Mattei, Rogério Clemente, and Paulo Henrique Pires Aguiar.Treatment of Large and Giant Residual and Recurrent Vestibular Schwannomas. Skull Base. 2007 Mar; 17(2): 109–117. Prepublished online 2006 Nov 1. doi: 10.1055/s-2006-953510
XinweiLi,GuohuaZhong,XueyingXu,KunWang,YinxinZhu,XuchenQi,JunhuiLv,YirongWang,SenShao. Surgical strategies for peripheral nerve schwannoma based on the intraoperative neurophysiological monitoring. Laparoscopic, Endoscopic and Robotic Surgery. Volume 2, Issue 3, September 2019, Pages 65-69.
Carlos Moreno-García,María Asunción Pons-García, Raúl González-García, and Florencio Monje-Gil. J Maxillofac Oral Surg.Schwannoma of Tongue. 2014 Jun; 13(2): 217–221. Published online 2011 Mar 25. doi: 10.1007/s12663-010-0101-0
Tamgadge Avinash, Tamgadge Sandhya, ShashibhushanDodal, Mayura Chande, and Treville Pereira. Recurrent Ancient Intraosseous Neurilemmoma of Maxilla: A Rare Case Report. Iran J Pathol. 2016 Spring; 11(2): 176–180.
Ankur Majumder, Arvind Ahuja, DS Chauhan, Purnima Paliwal, and Minakshi Bhardwaj. A clinicopathological study of peripheral schwannomas. Med Pharm Rep. 2021 Apr; 94(2): 191–196. Published online 2021 Apr 29. doi: 10.15386/mpr-1708.
José Antonio Galbiatti, Gabriel Rodrigues dos Santos Milhomens, Lara Giovanetti Bertozzo, Letícia Escames, Pedro de Alcântara Milhomens Neto, and Marilia Gabriela Palacio Galbiatti. Retrospective Analysis of 20 Patients Affected by Schwannomas in the Upper and Lower Limbs. Rev Bras Ortop (Sao Paulo). 2020 Oct; 55(5): 629–636. Published online 2020 Apr 6. doi: 10.1055/s-0040-1702962.
Swati Parhar, Harkanwal Preet Singh, Amit Nayyar, and Adesh S Manchanda. Intra-Oral Schwannoma- A Case Report. J Clin Diagn Res. 2014 Mar; 8(3): 264–265. Published online 2014 Mar 15. doi: 10.7860/JCDR/2014/7466.4181
M. Panduranga Kamath, Hema Kini,S.Vijendra Shenoy, D. Deviprasad, Nidhin Prakash, Radha Pai. Schwannoma of the base of tongue – A rare presentation. Egyptian Journal of Ear, Nose, Throat and Allied Sciences (2014) 15, 61–64
Williams H.K., Cannell H., Silvester K., Williams D.M. Neurilemmoma of the head and neck. Br. J. Oral Maxillofac. Surg. 1993; 31:32–35.
9. Lucas R.B. Pathology of Tumors of the Oral Tissue. 1984. New York, NY: Churchill Livingstone.
Wright B.A., Jackson D. Neural tumors of the oral cavity: a review of the spectrum of benign and malignant oral tumors of the oral cavity and jaws. Oral Surg. Oral Med. Oral Pathol. 1980;49: 509–522.
Shannon Coy, Rumana Rashid, Anat Stemmer-Rachamimov, and Sandro Santagata. An update on the CNS manifestations of neurofibromatosis type 2. Acta Neuropathol. 2020; 139(4): 643–665. Published online 2019 Jun 4. doi: 10.1007/s00401-019-02029-5.
Gainza-Cirauqui M.L., Eguía-Del Valle A., Martínez-Conde R., Coca-Meneses J.C., Aguirre-Urizar J.M. Ancient schwanomma of the hard palate. An uncommon case report and review. J Clin Exp Dent. 2013;5: e62–e65.
Jacob Pe’er. Pathology of eyelid tumors. Indian J Ophthalmol. 2016 Mar; 64(3): 177–190. doi: 10.4103/0301-4738.181752.
Abhishek Jaiswal, Asit Ranjan Mridha, Devajit Nath, Ashu Seith Bhalla, and Alok Thakkar. Intraparotid facial nerve schwannoma: A case report. World J Clin Cases. 2015 Mar 16; 3(3): 322–326. Published online 2015 Mar 16. doi: 10.12998/wjcc.v3.i3.322
Kun Z., Qi D.Y., Zhang K.H. A comparison between the clinical behavior of neurilemmomas in the neck and oral and maxillofacial region. J. Oral Maxillofac. Surg. 1993;51: 769–771.
F.J. Wippold, II, M. Lubner, R.J. Perrin, M. Lämmle, and A. Perry. Neuropathology for the Neuroradiologist: Antoni A and Antoni B Tissue Patterns. AJNR Am J Neuroradiol. 2007 Oct; 28(9): 1633–1638. doi: 10.3174/ajnr.A0682.
S Simonetti, C Serrano, J Hernández-Losa, S Bagué, R Orellana, C Valverde, M E Lleonart, M Aizpurua, J Carles, S Ramón y Cajal, C Romagosa. Schwannomas, benign tumors with a senescent phenotype. HistolHistopathol. 2014 Jun;29(6):721-30. doi: 10.14670/HH-29.721. Epub 2013 Nov 12.
Rodriguez F.J. Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems. Acta Neuropathol. 2012;123: 295–319.
Bansal R., Trivedi P., Patel S. Schwannoma of the tongue. Oral Oncol. Extra. 2005; 41:15–17.
Published
2022-04-11
How to Cite
KADHIM, M. A. A., AHMED, A. M., & SELIVANY, B. J. (2022). SOFT PALATE SCHWANNOMA: A CASE REPORT. Journal of Duhok University, 25(1), 43-48. https://doi.org/10.26682/sjuod.2022.25.1.7
Section
Pure and Engineering Sciences
It is the policy of the Journal of Duhok University to own the copyright of the technical contributions. It publishes and facilitates the appropriate re-utilize of the published materials by others. Photocopying is permitted with credit and referring to the source for individuals use.
Copyright © 2017. All Rights Reserved.
